Ayurmed Info

Manasamitra Vatakam Benefits, Dosage, Ingredients And Side Effects

Manasamitra Vatakam is a tablet, used in Ayurvedic treatment of psychiatric conditions, to improve intelligence, speech problems, etc. It is prepared from a combination of 73 ingredients. This medicine should only be taken under strict medical supervision. This medicine is formulated based on Kerala Ayurveda principles. 


Manasamitra tablet uses:

It is used in Ayurvedic treatment of depression and psychosis.
It is used in children to improve brain functions, memory and concentration, in diseases like autism.
It is used to treat epilepsy, seizures and mania.
It is also used in poison treatment.
There are many research articles written on this medicine to prove its efficacy as a neuro protective medicine.


Doctors also prescribe this for the treatment of
Adult autism
Insomnia, sleep disturbances
Schizophrenia, paranoia,
Panic attack, Panic disorders, Phobia, Manic depressive psychosis
Weak nervous system, nervous shivering, nervous speech problems

Effect on Tridosha – balances Vata, Pitta and Kapha.

Dose and Adjuvants

Manasamitra Vati dosage: 

1 – 2 tablets once or twice a day, before or after food or as directed by Ayurvedic doctor. It is traditionally given along with milk.

Adjuvants: Warm cow’s milk or Brahmi gritham or Mahakalyanaka gritham, Saraswatha gritham.

How long to use?
It can be used for a period of  6 months to one year or even longer, based on your doctor’s advice.

Can manasamithram be taken soon after food?
Ideally it is taken after 10 – 20 minutes after food. It can also be taken soon after food.

With western medicines
Seek your doctor’s advice if you are taking this product along with other western (allopathic/modern) medicines. Some Ayurvedic herbs can interact with modern medicine.
If both Ayurvedic and allopathic medicines are advised together, then it is best to take allopathic medicine first, wait for 30 minutes and then, after a gap of 15 – 30 minutes, take Ayurvedic medicine or as directed by the physician.

Can this be used while taking Homeopathic medicine?
Yes. This product does not react with homeopathic medicine.

With supplements like multivitamin tablets, Omega 3 fatty acids etc?
Yes. Generally, this product goes well with most of the dietary supplements. However, if you are taking more than one product per day, please consult your doctor for an opinion.

Can it be taken after 70 years of age?
Yes, but after 70, usually there are health complaints. Hence, it is better to use it after consulting an Ayurvedic doctor.

Can it be given to a child with adhd / autism or to improve concentration?
In severe cases of adhd and autism, it is advised by some Ayurvedic doctors. For use in children, doctor’s direct advice is highly necessary.
For memory, immunity and concentration improvement, there are better medicines such as Swarna Bindu Prashana and Swarna Vacha

Does Manasa mitra help with Alzheimer’s? My relative has been taking it for some time. They claim it helps with memory loss.
It is partially useful in Alzheimer’s disease. Usually other medicines such as Smriti Sagar ras, Saraswatarishtam, Brahmi Ghritham, Naladadi ghritham etc. are advised along with it by many Ayurvedic doctors. 

Side Effects

It should be used only under medical supervision. Over dosage may cause burning sensation in stomach.
Keep out of reach and sight of children. Store in cool dry place.
Some people  may experience worsening of mood and increase of anxiety.
This product is not habit forming. But it is generally advised not to stop this all of a sudden. The stopping should happen very gradually.

Over-dosage- A dose of 6 tablets per day  has caused palpitation and stomach burning sensation in a patient (see in the comment section below).


Kottakkal – Arya Vaidya Sala,
Amruta Drugs, Vaidyaratnam
Nagarjuna – Maanasamithra Vatakam

Some companies manufacture the same product by skipping the Swarna Bhasma (Gold) ingredient.

Expiry date

 Five years from the date of manufacture. Once after opening the container, it is better to empty it before an year.

How long does it take to start showing results?
Depends on the dosage and other products suggested with this. Usually 1 – 2 weeks time.

Can this product be taken along with Allopathic medicines (English medicines)?
It may react with some medicines. Consult your doctor for the right advice. When English and Ayurvedic medicines are advised together, it is best to take English medicine first, give a gap of half an hour and then take Ayurvedic medicines.  

Can it be used in people with diabetes?
Yes. But an eye should be kept on the blood sugar level. Your doctor should help you in this regard. This product can reduce blood sugar levels.

It is sold in plastic bottles. Is it fine? 
If the quality of the bottle material is very good, it should not be problem, if stored for a short period of time.

Can this be taken without consulting a doctor?
No. In many cases, this product alone might not work. More often this is given in combination with a few Ayurvedic medicines. Your Ayurveda practitioner will be the best judge to decide on those things.

Can one take non vegetarian food while taking this medicine?
Yes, unless your practitioner has asked to avoid it.

Is there any Pathya (diet rules to be followed while taking this product?
No product specific diet is mentioned. If the practitioner has advised diet control based on disease, one has to follow that.

Can this be taken while taking multivitamin tablets?
Yes, generally. Your consulting doctor will be good judge on this topic.

For High BP patient?

Can it be taken by a person with high blood pressure?
Dr JV Hebbar: 
Manasamitra vatakam is an Ayurvedic medicine, used for treating psychiatric disorders such as stress, depression etc. It also improves sleep. It contains many ingredients that are useful to maintain healthy blood pressure – such as 
Pravala Pishti – coral calx 
Prishniparni – Uraria picta 
Swarna Bhasma – Gold Calx 
Triphala, Brihati, Kantakari etc. 
Hence, this can be taken by a person with hypertension to control anger, stress, and to treat psychiatric disorders.


Manasamitra Vatakam ingredients, how to make:
10 g of each of
Bala – Country mallow (root) – Sida cordifolia
Nagabala – Grewia populifolia
Bilva – Bael (root) – Aegle marmelos
Prishniparni – Uraria picta
Pravala pishti – Coral
Shankhapushpi – Clitorea ternatea
Tamrachuda Padika
Swarna Bhasma

Pushkaramoola – Inula racemosa
Mrigashringa Bhasma  – Bhasma made of deer horn
Vacha – Acorus calamus
Tapya – Makshika Bhasma – Bhasma of Copper-Iron Pyrite
Chandana – Sandalwood – Santalum album
Raktachandana – Pterocarpus santalinus
Mukta Pishti – Paste prepared from Pearl – A traditional Ayurvedic medicine for the treatment of mental issues, stomach upset and Pitta problems. It helps to have a calm mind.
Loha Bhasma – Bhasma prepared from Iron
Madhuka – Licorice – Glycyrrhiza glabra

Twak – Cinnamon – Cinnamomum zeylanicum
Magadhi – Long pepper fruit – Piper longum
Ghanasara – Karpoora – Camphor – Cinnamomum camphora
Aileya – Prunus cerasus
Vishala – Citrullus cholocynthis
Nirgundi – Vitex negundo
Plava – Nyctanthes arbor-tristis
Rasna – Pluchea lanceolata / Vanda roxburghi
Rajata Bhasma – Bhasma of silver
Shilajatu – Asphaltum
Gojihva – Onosma bracteatum

Padmakeshara – Lotus – Nelumbium speciosum
Jivaka –  Malaxis acuminata
Rishabhaka – Manilkara hexandra (Roxb.) Dubard / Mimusoops hexandra Roxb.
Kakoli – Fritillaria roylei
Kshira Kakoli – Roscoea purpurea
Brihati – Indian Nightshade (root) – Solanum indicum
Kantakari – Yellow berried nightshade (whole plant) – Solanum xanthcarpum
Shravani, Mahashravani – Sphaeranthus indicus
Bhunimba – The Creat (whole plant) – Andrographis paniculata
Kritamala – Cassia fistula
Parushaka – Grewia asiatica

Haritaki – Chebulic Myrobalan fruit rind – Terminalia chebula
Vibhitaki – Belliric Myrobalan fruit rind – Terminalia bellirica
Amalaki – Indian gooseberry fruit – Emblica officinalis Gaertn.
Amruta – Indian Tinospora (stem) – Tinospora cordifolia
Shweta and Krishnasariva – Indian Sarsaparila – Hemidesmus indicus
Jivanti – Leptadenia reticulata
Somavalli – Sarcostemma acidum
Ashwagandha – Winter cherry/ Indian Ginseng (root) – Withania somnifera (L.) Dunal.
Nisha – Turmeric (Rhizome) – Curcuma longa
Usheera – Khus Khus – Vetiveria zizanioides
Draksha – Raisin – Vitis vinifera
Yashti – Licorice – Glycyrrhiza glabra
Riddhi – Vigna cylindrica
Durva – Bermuda grass – Cynodon dactylon

Hamsapadi – Adiantum philippense Linn. / lunulatum
Bhadra – Sida cordifolia
Lavanga – Clove – Syzygium aromaticum
Tulasi – Holy Basil – Ocimum sanctum
Kasturi – Musk
Kumkuma – Saffron – Crocus sativus

Quantity Sufficient of each of  –
Juice extract of Trayamana – Gentiana kurroo
Water decoction of
Shankhapushpi – Convolvulus pluricaulis
Vacha – Acorus calamus
Sariva – Indian Sarsaparila – Hemidesmus indicus
Lakshmana – Ipomoea sepiaria / Biophytum sensitivum
Bilva – Bael (root) – Aegle marmelos
Bala – Country mallow (root) – Sida cordifolia
Goksheera – Cow milk
Jiraka – Cumin – Cuminum cyminum
Somavalli – Sarcostemma acidum
Stanya – breast milk.

The fine powder of herbal powder mix is ground with the liquids and a paste is prepared, which is made into tablet form, dried and preserved.

Shloka, Sanskrit Verse

Diet To Follow

Have more of Ghee, coconut oil, Sunflower seed, almond, taro root, flaxseed oil, soyabean, pistachio,
Broccoli, carrots, chard, nuts, papaya, pumpkin, red peppers
Flax seeds, walnut, tofu, brussel sprout, cauliflower, winter squash, fish oil, egg oil, krill oil, chia seeds, camelia are fine to take.

Diet To avoid:
There are no diet restrictions. Please avoid all types of junk foods, excessive non veg foods, try to avoid or limit alcohol and smoking. Avoid aerated drinks.
Please prefer homemade food wherever possible.


 Sahasrayoga Gutika prakarana 68, AFI Vol 1


General anxiety disorder – GAD – 
Department of Neurophysiology, National Institute of Mental Health and Neurosciences (NIMHANS Deemed University), Bangalore, conducted a clinical research on this product on generalized anxiety disorder. 72 patients participated in the clinical trial. The study found that the product is effective in the management GAD with comorbid generalized social phobia. (1)

Neuro-protective study on MMV
Department of Pharmacology, C.L. Baid Metha College of Pharmacy and Research Foundation, Tamilnadu, India. conducted an animal experimental study on Manasamitra vati tablet on Neuroprotective effect of Manasamitra vatakam against aluminium induced cognitive impairment and oxidative damage in the cortex and hippocampus of rat brain. The study concluded that MMV is very effective in protecting the brain from hazardous chemicals. (2)

Habit forming

Is this medicine habit forming? Does it create dependence? Can we stop it after a few months of usage?
This medicine is not habit forming. After using for the prescribed period, your doctor would gradually decrease the dose and eventually stop it. Follow your doctor’s instructions for gradual decrease of dose and stopping. Usually it does not cause any ill effects.

Manasamitra Vatakam before exams?

Please consult your doctor before taking this medicine.
This article is written by Dr. Janardhana V Hebbar BAMS, MD (Ayu), PGDPSM, Managing Director, Easy Ayurveda Hospital.
It is reviewed by Dr. Raviganesh Mogra BAMS, MD (Ayu), Chief Medical Officer, Easy Ayurveda Hospital

139 thoughts on “Manasamitra Vatakam Benefits, Dosage, Ingredients And Side Effects”

  1. hi iam tharun i need manasa mitra vatakam.which is the best company manufacturing this tablets,is dis available in AP if so where.please mail yo me
    Thank You

  2. Here in the US, the heavy metal issue is used to scare us off Ayurvedic medicines. You mention heavy metals in this formulation. Would you please tell me what ingredient you are referring to and whether the metals are there by design or through contamination?

    Should people who are less able to detoxify heavy metals avoid these?

    Many thanks!

    • Dear Mary,
      There are no heavy metals in Manasamitra Vatakam. But there are a few Bhasmas (Calx / microfine powder). Like Gold and Silver Bhasma (calx). They are there by design. In this particular product, it can be had my those who are less able to detoxify heavy metals.
      On a general note, a few of Ayurvedic medicines contain heavy metals like mercury by design. But the dose is very very low and they are used for a specific time period with a specific dose. An Ideal Ayurveda doctor would reveal such a fact to his patient, while prescribing.

  3. Both are same. How long to take depends on your response to the treatment and doctor’s advice. Usually a treatment of 2 – 6 months might be required, with gradual reduction in dosage.

  4. I took Manas Mitra vatakam for 2 months but had some side effects. Body heat seem to increase considerably and led to burining senation during urination and blood? I was on 2X tablets bed time,, had them with water. Please suggest any alternative to MMV?

  5. Hello Dr Hebbar,
    Is it ok to take this medicine for more than six months at a time (even under doctor supervision). What are the long term side effects of this medicine

  6. Sir I m prescribed with this tablet along with a combination of ashwagandharishtam balarishtam anddasamoollaristam for anxiety but I feel anxious through out the day

  7. Hello Dr Hebbar, I was told to take Manasamitra Vatakam by a Dr in India who said it would be fine to take it with my Anti-depressants. I’ve noticed I have become more anxious than usual so am wondering should I take it at night instead of the morning?

  8. Bonjour monsieur,voila j’ai acheté sur le site ayuvedaforall.com le médicament Manasamitra Vatakam que m’a prescrit mon médecin .Seulement le médicament que j’ai recu contient 53 ingrédients alors que celui indiqué sur le site et que j’ai commande en contient normalement 73 ingréédients.Il vient de la fabrique “Vaidyaratnammooss.com.la connaissez vous?Pouvez vous m’indiquer ou je puisse commander le vrai médicament de 73 ingrédients s’il vous plait.C’est trés important pour moi.J’habite en france et suis obliger de passer par internet.Merci de me répondre
    Mme Toutirais Josiane.

    • Bonjour,
      Vaidyaratnammooss.com est une très bonne compagnie. Ils pourraient tout simplement ont sauté de mentionner tous les ingrédients en raison de manque d’espace. Je vous suggère de continuer à l’utiliser. La prochaine fois, s’il vous plaît acheter des médicaments de indiaabundance.com je les connais personnellement et sont très bons, des gens d’un esprit de service.

  9. Whether Manasmithram Gulika by Vaidyratnam oushadhashala (based on Ashtangahridayam) is equivalent in effect to Manasmitravatakam by kotakkal. I have been prescribed Manasmitravatakam by ayurvedic doctor for anxiety/depression.Vaidyaratnam was locally available.If there is qualitative difference I will definitely prefer better one.Please advise. Thanks and regards Girish Agarwal Haridwar

  10. There is an avp shop in karol bagh and also a kottakal shop in karol bagh delhi. Not sure where in northindia u r from or order online at ayurvedaforall.com

  11. My daughter has been diagnosed with autism. A doctor prescribed manasamitra vatakam to begin from May. Once started, within how long can we expect to see a difference?

  12. Sir i’m using nagarjuna manasamitra vattakam frm 2 months, i’m addict to smoking frm past 5years, it cause any effects? I hve lack of concentration, i cnt concentrate to anything more tham 2mins plz help me sir

  13. Dear Dr JV Hebbar,

    Your website is very helpful and informative.The question we have is how to choose
    an Ayurveda doctor in our area,since there are so many?We live in Toronto Canada,
    but could go also to USA.

    Thank you very much!


  14. Hello Sir,i,m ashwini hebbar..sir mujhe 3saal se neend ki takleef he.or pet ki bhi takleef he.pet to hamesha kharab rehetha he.or neend ka sub se bada problem he.sir full night ek min bhi neend nahi ati.kya karu samhaj me nahi ata.din bhar isi ki chinta padi reheti he.plz me konsi medicine le sakti hoo.sir plz

    • hello, aapke dono problems ek dusre se related hai. dononka agar teek tharah se samadhan huva tho accha hai. sirf yehi ek medicine aapke liye kafi nahi hoga. aur bhi davaye hai jo aapke kaam aasakthe hai jiske liye aapko apne nazdeeki Ayurvedic doctor se milna hoga. aur ek baath, davayiyonke saath aap apne khaane-peene ke habit me control rakhna chahiye aur thoda bahuth yoga, pranayama, dhyana kare tho bahuth behthar hoga.

  15. Hi, as you may have gone through side effects of manasamitra vatakam, overdose may cause severe gastic irritation and bleeding in gastrum also. So, it is better to consult your doctor at the earliest and confirm the dosage you have taken is right.

  16. hi,
    you can take mentat along with after consulting your Ayurvedic doctor again.
    you can surely get very good results but can not assure you complete cure unless we analyse your condition personally.

    • Manasamitra is commonly used in treating depression, psychiatric conditions etc. Saraswatarishta is also used in depression but is more popular as a brain tonic, suitable for all ages.

  17. Hi Doctor,
    I have been diagnosed with generalised anxiety disorder. Been about 5 years and I am now thinking about medication. My doctor has prescribed manasmitra vati
    I am finding good relief. I just have one question , will my anxiety come back as soon as I stop this medication? Or does it cure the problem


  18. Sir,

    I have this acid reflux problem, i am suggested dasamoolorishtam and ashwagandharishtam 15+15 ml together with water and dhanvantara gutika. Also I have anxiety disorders, Manasamitra gulika 1 no. bed time. Pls, review my medicines.


  19. Hi…sir I have obessive compulsive disorder problem.so I consulted ayurvedic doctor one week before and they suggested mahakalyanaka ghruta,m anasamitra various,and himasagara taila.d ear sir, how does it works on ocd? In how many days I can get re from ocd?

  20. Hi sir, I have ocd problem since many years.Recently I met one ayurvedic doctor and he prescribed manasamitra vati and another one gruta and himasagara taila.in how many days I can get cure?

  21. Is it good to have manasamitravatakam only when you feel anxious and depressed instead of taking them daily. I find relief after one or two hours after taking this medicine.

  22. Dear Dr. Hebbar Sir,
    I use Manasamitra vatakam, every night at bed time. It has given lot of relief from anxiety disorders. Great advice from your good self, thanks and Lord Krishna give all the best comforts to you sir.


  23. Dear Dr
    MMV if stopped abruptly after 2 months in a 22 yrs old female will lead to anxiety symptoms returning? The patient does not get her periods regularly. Will MMV affect the cycles? Will MMV cause weight gain?